Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle

Adeno-associated virus (AAV) is being developed as a vector capable of conferring long-term gene expression, which is useful in the treatment of chronic diseases. In most therapeutic applications, it is necessary to readminister the vector. This study characterizes the humoral immune response to AAV...

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Vydáno v:	J Virol
Hlavní autoři:	Chirmule, Narendra, Xiao, Weidong, Truneh, Alemseged, Schnell, Michael A., Hughes, Joseph V., Zoltick, Philip, Wilson, James M.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2000
Témata:	Gene Therapy
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111724/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666273/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2420-2425.2000
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