Hybrid Vectors Based on Adeno-Associated Virus Serotypes 2 and 5 for Muscle-Directed Gene Transfer

Vectors based on hybrids consisting of adeno-associated virus types 2 (ITRs and Rep) and 5 (Cap) were evaluated for muscle-directed gene transfer (called AAV2/5). Evaluation in immune-competent mice revealed greater transduction efficacy with AAV2/5 than with AAV2 and no cross-neutralization between...

Description complète

Détails bibliographiques

Publié dans:	J Virol
Auteurs principaux:	Hildinger, Markus, Auricchio, Alberto, Gao, Guangping, Wang, Lili, Chirmule, Narendra, Wilson, James M.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 2001
Sujets:	Gene Therapy
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6199-6203.2001
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!