Adeno-Associated Virus as a Vector for Liver-Directed Gene Therapy

Factors relevant to the successful application of adeno-associated virus (AAV) vectors for liver-directed gene therapy were evaluated. Vectors with different promoters driving expression of human α-1-antitrypsin (α-1AT) were injected into the portal circulation of immunodeficient mice. α-1AT express...

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Hlavní autoři: Xiao, Weidong, Berta, Scott C., Lu, Min Min, Moscioni, A. David, Tazelaar, John, Wilson, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1998
Témata:
Gene Therapy
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC110575/
https://ncbi.nlm.nih.gov/pubmed/9811765
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