Adeno-Associated Virus as a Vector for Liver-Directed Gene Therapy

Factors relevant to the successful application of adeno-associated virus (AAV) vectors for liver-directed gene therapy were evaluated. Vectors with different promoters driving expression of human α-1-antitrypsin (α-1AT) were injected into the portal circulation of immunodeficient mice. α-1AT express...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Xiao, Weidong, Berta, Scott C., Lu, Min Min, Moscioni, A. David, Tazelaar, John, Wilson, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Gene Therapy
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110575/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10222-10226.1998
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