Hybrid Vectors Based on Adeno-Associated Virus Serotypes 2 and 5 for Muscle-Directed Gene Transfer

Vectors based on hybrids consisting of adeno-associated virus types 2 (ITRs and Rep) and 5 (Cap) were evaluated for muscle-directed gene transfer (called AAV2/5). Evaluation in immune-competent mice revealed greater transduction efficacy with AAV2/5 than with AAV2 and no cross-neutralization between...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Hildinger, Markus, Auricchio, Alberto, Gao, Guangping, Wang, Lili, Chirmule, Narendra, Wilson, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 2001
Assuntos:	Gene Therapy
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114336/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390622/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.13.6199-6203.2001
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!