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Porphyrin-substrate binding to murine ferrochelatase: effect on the thermal stability of the enzyme

Ferrochelatase (EC 4.99.1.1), the terminal enzyme of the haem biosynthetic pathway, catalyses the chelation of Fe(II) into the protoporphyrin IX ring. The energetics of the binding between murine ferrochelatase and mesoporphyrin were determined using isothermal titration calorimetry, which revealed...

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Bibliografische gegevens
Hoofdauteurs: Franco, Ricardo, Bai, Guangyue, Prosinecki, Vesna, Abrunhosa, Filipa, Ferreira, Gloria C., Bastos, Margarida
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Portland Press Ltd. 2005
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134880/
https://ncbi.nlm.nih.gov/pubmed/15496139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040921
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