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Porphyrin-substrate binding to murine ferrochelatase: effect on the thermal stability of the enzyme
Ferrochelatase (EC 4.99.1.1), the terminal enzyme of the haem biosynthetic pathway, catalyses the chelation of Fe(II) into the protoporphyrin IX ring. The energetics of the binding between murine ferrochelatase and mesoporphyrin were determined using isothermal titration calorimetry, which revealed...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1134880/ https://ncbi.nlm.nih.gov/pubmed/15496139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20040921 |
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