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BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II
Mammalian cells exhibit a complex response to DNA damage. The tumor suppressor BRCA1 and associated protein BARD1 are thought to play an important role in this response, and our previous work demonstrated that this includes transient inhibition of the pre-mRNA 3′ processing machinery. Here we provid...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1132008/ https://ncbi.nlm.nih.gov/pubmed/15905410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1309505 |
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