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PARN deadenylase is involved in miRNA-dependent degradation of TP53 mRNA in mammalian cells
mRNA deadenylation is under the control of cis-acting regulatory elements, which include AU-rich elements (AREs) and microRNA (miRNA) targeting sites, within the 3′ untranslated region (3′ UTRs) of eukaryotic mRNAs. Deadenylases promote miRNA-induced mRNA decay through their interaction with miRNA-i...
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| Publicado no: | Nucleic Acids Res |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4678859/ https://ncbi.nlm.nih.gov/pubmed/26400160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv959 |
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