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BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II
Mammalian cells exhibit a complex response to DNA damage. The tumor suppressor BRCA1 and associated protein BARD1 are thought to play an important role in this response, and our previous work demonstrated that this includes transient inhibition of the pre-mRNA 3′ processing machinery. Here we provid...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1132008/ https://ncbi.nlm.nih.gov/pubmed/15905410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1309505 |
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