BRCA1/BARD1 inhibition of mRNA 3′ processing involves targeted degradation of RNA polymerase II

Mammalian cells exhibit a complex response to DNA damage. The tumor suppressor BRCA1 and associated protein BARD1 are thought to play an important role in this response, and our previous work demonstrated that this includes transient inhibition of the pre-mRNA 3′ processing machinery. Here we provid...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kleiman, Frida E., Wu-Baer, Foon, Fonseca, Danae, Kaneko, Syuzo, Baer, Richard, Manley, James L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2005
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132008/
https://ncbi.nlm.nih.gov/pubmed/15905410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1309505
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak