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The basal-like mammary carcinomas induced by Brca1 or Bard1 inactivation implicate the BRCA1/BARD1 heterodimer in tumor suppression

Women with germ-line mutations of the BRCA1 tumor suppressor gene are highly susceptible to breast and ovarian cancer. The protein product of BRCA1 is involved in a broad spectrum of biological processes and interacts with many diverse proteins. One of these, BARD1, associates with BRCA1 to form a h...

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Bibliografski detalji
Glavni autori: Shakya, Reena, Szabolcs, Matthias, McCarthy, Ellen, Ospina, Elson, Basso, Katia, Nandula, Subhadra, Murty, Vundavalli, Baer, Richard, Ludwig, Thomas
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365565/
https://ncbi.nlm.nih.gov/pubmed/18443292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711032105
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