Requirements of the RNA Polymerase II C-Terminal Domain for Reconstituting Pre-mRNA 3′ Cleavage

RNA polymerase II (RNAP II) has previously been shown to be required for the pre-mRNA polyadenylation cleavage reaction in vitro. This activity was found to reside solely in the C-terminal domain (CTD) of the enzyme's largest subunit. Using a deletion analysis of glutathione S-transferase-CTD f...

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Detalhes bibliográficos
Main Authors: Ryan, Kevin, Murthy, Kanneganti G. K., Kaneko, Syuzo, Manley, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC135617/
https://ncbi.nlm.nih.gov/pubmed/11865048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.22.6.1684-1692.2002
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