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Kin28, the TFIIH-Associated Carboxy-Terminal Domain Kinase, Facilitates the Recruitment of mRNA Processing Machinery to RNA Polymerase II

The cotranscriptional placement of the 7-methylguanosine cap on pre-mRNA is mediated by recruitment of capping enzyme to the phosphorylated carboxy-terminal domain (CTD) of RNA polymerase II. Immunoblotting suggests that the capping enzyme guanylyltransferase (Ceg1) is stabilized in vivo by its inte...

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Auteurs principaux: Rodriguez, Christine R., Cho, Eun-Jung, Keogh, Michael-C., Moore, Claire L., Greenleaf, Arno L., Buratowski, Stephen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC85066/
https://ncbi.nlm.nih.gov/pubmed/10594013
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