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Structure-Based Mutagenesis Study of Hepatitis C Virus NS3 Helicase

The NS3 protein of hepatitis C virus (HCV) is a bifunctional protein containing a serine protease in the N-terminal one-third, which is stimulated upon binding of the NS4A cofactor, and an RNA helicase in the C-terminal two-thirds. In this study, a C-terminal hexahistidine-tagged helicase domain of...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Lin, Chao, Kim, Joseph L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482634/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8798-8807.1999
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