Structure-Based Mutagenesis Study of Hepatitis C Virus NS3 Helicase
The NS3 protein of hepatitis C virus (HCV) is a bifunctional protein containing a serine protease in the N-terminal one-third, which is stimulated upon binding of the NS4A cofactor, and an RNA helicase in the C-terminal two-thirds. In this study, a C-terminal hexahistidine-tagged helicase domain of...
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| Pubblicato in: | J Virol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology (ASM)
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC112901/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10482634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.10.8798-8807.1999 |
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