Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase

Interaction between viral proteins is necessary for viral replication and viral particle assembly. We used the yeast two-hybrid assay to identify interactions among all the mature proteins of the hepatitis C virus. The interaction between NS3 and NS3 was one of the strongest viral protein-protein in...

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Detalhes bibliográficos
Main Authors: Khu, Yee-Ling, Koh, Esther, Lim, Siew Pheng, Tan, Yin Hwee, Brenner, Sydney, Lim, Seng Gee, Hong, Wan Jin, Goh, Phuay-Yee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC113914/
https://ncbi.nlm.nih.gov/pubmed/11119590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.1.205-214.2001
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