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Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3′-Terminal Sequences of Viral Positive- and Negative-Strand RNA

The hepatitis C virus (HCV)-encoded protease/helicase NS3 is likely to be involved in viral RNA replication. We have expressed and purified recombinant NS3 (protease and helicase domains) and ΔpNS3 (helicase domain only) and examined their abilities to interact with the 3′-terminal sequence of both...

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Bibliografiske detaljer
Main Authors: Banerjee, Rajeev, Dasgupta, Asim
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114080/
https://ncbi.nlm.nih.gov/pubmed/11160669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.4.1708-1721.2001
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