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Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3′-Terminal Sequences of Viral Positive- and Negative-Strand RNA

The hepatitis C virus (HCV)-encoded protease/helicase NS3 is likely to be involved in viral RNA replication. We have expressed and purified recombinant NS3 (protease and helicase domains) and ΔpNS3 (helicase domain only) and examined their abilities to interact with the 3′-terminal sequence of both...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Banerjee, Rajeev, Dasgupta, Asim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114080/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.4.1708-1721.2001
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