Incorporation of Adeno-Associated Virus in a Calcium Phosphate Coprecipitate Improves Gene Transfer to Airway Epithelia In Vitro and In Vivo

Eitemau Tebyg

• Incorporation of adenovirus in calcium phosphate precipitates enhances gene transfer to airway epithelia in vitro and in vivo.
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• Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus
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  Cyhoeddwyd: (2000)
• Adeno-Associated Virus Type 5 (AAV5) but Not AAV2 Binds to the Apical Surfaces of Airway Epithelia and Facilitates Gene Transfer
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  Cyhoeddwyd: (2000)
• Apical Localization of the Coxsackie-Adenovirus Receptor by Glycosyl-Phosphatidylinositol Modification Is Sufficient for Adenovirus-Mediated Gene Transfer through the Apical Surface of Human Airway Epithelia
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  Cyhoeddwyd: (2001)
• A shortened adeno-associated virus expression cassette for CFTR gene transfer to cystic fibrosis airway epithelia
  gan: Ostedgaard, Lynda S., et al.
  Cyhoeddwyd: (2005)