Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus
The restriction of viral receptors and coreceptors to the basolateral surface of airway epithelial cells has been blamed for the inefficient transfer of viral vectors to the apical surface of this tissue. We now report, however, that differentiated human airway epithelia internalize rAAV type-2 viru...
Kaydedildi:
| Yayımlandı: | J Clin Invest |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Clinical Investigation
2000
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8317 |
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