Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus

The restriction of viral receptors and coreceptors to the basolateral surface of airway epithelial cells has been blamed for the inefficient transfer of viral vectors to the apical surface of this tissue. We now report, however, that differentiated human airway epithelia internalize rAAV type-2 viru...

Ausführliche Beschreibung

Bibliografische Detailangaben

Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Duan, Dongsheng, Yue, Yongping, Yan, Ziying, Yang, Jusan, Engelhardt, John F.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 2000
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300848/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841516/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI8317
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!