Caricamento...

Apical Localization of the Coxsackie-Adenovirus Receptor by Glycosyl-Phosphatidylinositol Modification Is Sufficient for Adenovirus-Mediated Gene Transfer through the Apical Surface of Human Airway Epithelia

In well-differentiated human airway epithelia, the coxsackie B and adenovirus type 2 and 5 receptor (CAR) resides primarily on the basolateral membrane. This location may explain the observation that gene transfer is inefficient when adenovirus vectors are applied to the apical surface. To further t...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Walters, Robert W., van't Hof, Wouter, Yi, Su Min P., Schroth, Mary K., Zabner, Joseph, Crystal, Ronald G., Welsh, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC115005/
https://ncbi.nlm.nih.gov/pubmed/11462042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.16.7703-7711.2001
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !