DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination

Our previous studies have shown that isolated cytotoxic T lymphocyte (CTL), B-cell, and T-helper epitopes, for which we coined the term minigenes, can be effective vaccines; when expressed from recombinant vaccinia viruses, these short immunogenic sequences confer protection against a variety of vir...

詳細記述

書誌詳細

出版年:	J Virol
主要な著者:	Rodriguez, Fernando, An, Ling Ling, Harkins, Stephanie, Zhang, Jie, Yokoyama, Masayuki, Widera, Georg, Fuller, James T., Kincaid, Carrie, Campbell, Iain L., Whitton, J. Lindsay
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Microbiology (ASM) 1998
主題:	Viral Pathogenesis and Immunity
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.5174-5181.1998
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