DNA Immunization with Minigenes: Low Frequency of Memory Cytotoxic T Lymphocytes and Inefficient Antiviral Protection Are Rectified by Ubiquitination

Our previous studies have shown that isolated cytotoxic T lymphocyte (CTL), B-cell, and T-helper epitopes, for which we coined the term minigenes, can be effective vaccines; when expressed from recombinant vaccinia viruses, these short immunogenic sequences confer protection against a variety of vir...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Rodriguez, Fernando, An, Ling Ling, Harkins, Stephanie, Zhang, Jie, Yokoyama, Masayuki, Widera, Georg, Fuller, James T., Kincaid, Carrie, Campbell, Iain L., Whitton, J. Lindsay
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110091/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573289/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.5174-5181.1998
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!