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Induction of Antiviral Antibodies by DNA Immunization Requires neither Perforin-Mediated nor CD8(+)-T-Cell-Mediated Lysis of Antigen-Expressing Cells
DNA immunization induces antibodies to the encoded protein, which indicates that the protein must gain access to the extracellular milieu, allowing it to interact with naïve B lymphocytes. It has been suggested that antigen release may be effected by cytotoxic-T-lymphocyte-mediated lysis of transfec...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC104319/ https://ncbi.nlm.nih.gov/pubmed/10438882 |
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