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DNA immunization: Induction of higher avidity antibody and effect of route on T cell cytotoxicity

Immunizations of mice with plasmid DNAs encoding ovalbumin (OVA), human Ig, and hen egg lysozyme were compared with doses of soluble protein (without adjuvant) that induced similar IgG responses. The route of immunization influenced the magnitude of the antibody (Ab) response in that intradermal (i....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Boyle, Jefferey S., Silva, Anabel, Brady, Jamie L., Lew, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25074/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9405663/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.26.14626
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