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Mutagenesis by reversible promoter insertion to study the activation of NF-κB
Genetic dissection of signaling pathways in mammalian cells involves screening or selecting phenotypic mutants obtained by a variety of techniques. Limitations in current methods include inadequate genome coverage and difficulty in validating the link between mutation and phenotype. We describe an i...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1088393/ https://ncbi.nlm.nih.gov/pubmed/15851657 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502463102 |
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