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Regulation of NF-κB by NSD1/FBXL11-dependent reversible lysine methylation of p65

NF-κB, a central coordinator of immune and inflammatory responses, must be tightly regulated. We describe a NF-κB regulatory pathway that is driven by reversible lysine methylation of the p65 subunit, carried out by a lysine methylase, the nuclear receptor–binding SET domain-containing protein 1 (NS...

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Detalhes bibliográficos
Main Authors: Lu, Tao, Jackson, Mark W., Wang, Benlian, Yang, Maojing, Chance, Mark R., Miyagi, Masaru, Gudkov, Andrei V., Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806709/
https://ncbi.nlm.nih.gov/pubmed/20080798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912493107
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