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Use of Forward Genetics to Discover Novel Regulators of NF-κB

Forward and reverse genetic experiments have both played important roles in revealing critical aspects of mammalian signal transduction pathways in cell culture experiments. Only recently have we begun to comprehend the depth, breadth, and complexity of these pathways and of their interrelationships...

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Detalhes bibliográficos
Main Authors: Lu, Tao, Stark, George R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869522/
https://ncbi.nlm.nih.gov/pubmed/20516132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a001966
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