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Long-Distance Effects of Insertional Mutagenesis

BACKGROUND: Most common systems of genetic engineering of mammalian cells are associated with insertional mutagenesis of the modified cells. Insertional mutagenesis is also a popular approach to generate random alterations for gene discovery projects. A better understanding of the interaction of the...

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Detalhes bibliográficos
Main Authors: Singhal, Ruchi, Deng, Xiaotao, Chenchik, Alex A., Kandel, Eugene S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3016401/
https://ncbi.nlm.nih.gov/pubmed/21246045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015832
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