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Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers

Meropenem is a broad-spectrum carbapenem antibacterial agent. In order to optimize levels in plasma relative to the MICs, the ideal dose level and dosage regimen need to be determined. The pharmacokinetics of meropenem were studied in two groups, each comprising eight healthy volunteers who received...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Krueger, Wolfgang A., Bulitta, Jurgen, Kinzig-Schippers, Martina, Landersdorfer, Cornelia, Holzgrabe, Ulrike, Naber, Kurt G., Drusano, George L., Sörgel, Fritz
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087638/
https://ncbi.nlm.nih.gov/pubmed/15855510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1881-1889.2005
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