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Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers

Meropenem is a broad-spectrum carbapenem antibacterial agent. In order to optimize levels in plasma relative to the MICs, the ideal dose level and dosage regimen need to be determined. The pharmacokinetics of meropenem were studied in two groups, each comprising eight healthy volunteers who received...

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Detalhes bibliográficos
Main Authors: Krueger, Wolfgang A., Bulitta, Jurgen, Kinzig-Schippers, Martina, Landersdorfer, Cornelia, Holzgrabe, Ulrike, Naber, Kurt G., Drusano, George L., Sörgel, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087638/
https://ncbi.nlm.nih.gov/pubmed/15855510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1881-1889.2005
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