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Evaluation by Monte Carlo Simulation of the Pharmacokinetics of Two Doses of Meropenem Administered Intermittently or as a Continuous Infusion in Healthy Volunteers

Meropenem is a broad-spectrum carbapenem antibacterial agent. In order to optimize levels in plasma relative to the MICs, the ideal dose level and dosage regimen need to be determined. The pharmacokinetics of meropenem were studied in two groups, each comprising eight healthy volunteers who received...

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主要な著者: Krueger, Wolfgang A., Bulitta, Jurgen, Kinzig-Schippers, Martina, Landersdorfer, Cornelia, Holzgrabe, Ulrike, Naber, Kurt G., Drusano, George L., Sörgel, Fritz
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087638/
https://ncbi.nlm.nih.gov/pubmed/15855510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1881-1889.2005
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