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Penetration of Moxifloxacin into Bone Evaluated by Monte Carlo Simulation

Moxifloxacin is a fluoroquinolone with a broad spectrum of activity and good penetration into many tissues, including bone. Penetration of moxifloxacin into bone has not yet been studied using compartmental modeling techniques. Therefore, we determined the rate and extent of bone penetration by moxi...

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Main Authors: Landersdorfer, Cornelia B., Kinzig, Martina, Hennig, Friedrich F., Bulitta, Jürgen B., Holzgrabe, Ulrike, Drusano, George L., Sörgel, Fritz, Gusinde, Johannes
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2681494/
https://ncbi.nlm.nih.gov/pubmed/19223648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01056-08
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