Competitive Inhibition of Renal Tubular Secretion of Gemifloxacin by Probenecid

Probenecid interacts with transport processes of drugs at several sites in the body. For most quinolones, renal clearance is reduced by concomitant administration of probenecid. The interaction between gemifloxacin and probenecid has not yet been studied. We studied the extent, time course, site(s),...

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Главные авторы: Landersdorfer, Cornelia B., Kirkpatrick, Carl M. J., Kinzig, Martina, Bulitta, Jürgen B., Holzgrabe, Ulrike, Drusano, George L., Sörgel, Fritz
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2009
Предметы:
Pharmacology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737886/
https://ncbi.nlm.nih.gov/pubmed/19564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01200-08
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