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Competitive Inhibition of Renal Tubular Secretion of Gemifloxacin by Probenecid

Probenecid interacts with transport processes of drugs at several sites in the body. For most quinolones, renal clearance is reduced by concomitant administration of probenecid. The interaction between gemifloxacin and probenecid has not yet been studied. We studied the extent, time course, site(s),...

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Détails bibliographiques
Auteurs principaux: Landersdorfer, Cornelia B., Kirkpatrick, Carl M. J., Kinzig, Martina, Bulitta, Jürgen B., Holzgrabe, Ulrike, Drusano, George L., Sörgel, Fritz
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737886/
https://ncbi.nlm.nih.gov/pubmed/19564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01200-08
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