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Competitive Inhibition of Renal Tubular Secretion of Gemifloxacin by Probenecid

Probenecid interacts with transport processes of drugs at several sites in the body. For most quinolones, renal clearance is reduced by concomitant administration of probenecid. The interaction between gemifloxacin and probenecid has not yet been studied. We studied the extent, time course, site(s),...

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Detalhes bibliográficos
Main Authors: Landersdorfer, Cornelia B., Kirkpatrick, Carl M. J., Kinzig, Martina, Bulitta, Jürgen B., Holzgrabe, Ulrike, Drusano, George L., Sörgel, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2737886/
https://ncbi.nlm.nih.gov/pubmed/19564368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01200-08
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