Population Pharmacokinetics at Two Dose Levels and Pharmacodynamic Profiling of Flucloxacillin

Flucloxacillin is often used for the treatment of serious infections due to sensitive staphylococci. The pharmacokinetic (PK)-pharmacodynamic (PD) breakpoint of flucloxacillin has not been determined by the use of population PK. Targets based on the duration of non-protein-bound concentrations above...

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Hlavní autoři: Landersdorfer, Cornelia B., Kirkpatrick, Carl M. J., Kinzig-Schippers, Martina, Bulitta, Jürgen B., Holzgrabe, Ulrike, Drusano, George L., Sörgel, Fritz
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2007
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2043233/
https://ncbi.nlm.nih.gov/pubmed/17576847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01410-06
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