Inhibition of flucloxacillin tubular renal secretion by piperacillin

AIMS: To explore the extent, time course, site(s), mechanism and possible clinical relevance of the pharmacokinetic (PK) interaction between piperacillin and flucloxacillin. METHODS: A single-dose, randomized, six-way crossover study in 10 healthy volunteers where all subjects received all of the fo...

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Autors principals: Landersdorfer, Cornelia B, Kirkpatrick, Carl M J, Kinzig, Martina, Bulitta, Jürgen B, Holzgrabe, Ulrike, Sörgel, Fritz
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2008
Matèries:
Drug Interactions
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2661980/
https://ncbi.nlm.nih.gov/pubmed/19032173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2008.03266.x
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