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Competitive inhibition of renal tubular secretion of ciprofloxacin and metabolite by probenecid

AIMS: Probenecid influences transport processes of drugs at several sites in the body and decreases elimination of several quinolones. We sought to explore extent, time course, and mechanism of the interaction between ciprofloxacin and probenecid at renal and nonrenal sites. METHODS: A randomized, t...

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Detalhes bibliográficos
Main Authors: Landersdorfer, Cornelia B, Kirkpatrick, Carl M J, Kinzig, Martina, Bulitta, Jürgen B, Holzgrabe, Ulrike, Jaehde, Ulrich, Reiter, Andreas, Naber, Kurt G, Rodamer, Michael, Sörgel, Fritz
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2824478/
https://ncbi.nlm.nih.gov/pubmed/20233180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03564.x
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