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Structural basis for selectivity and toxicity of ribosomal antibiotics

Ribosomal antibiotics must discriminate between bacterial and eukaryotic ribosomes to various extents. Despite major differences in bacterial and eukaryotic ribosome structure, a single nucleotide or amino acid determines the selectivity of drugs affecting protein synthesis. Analysis of resistance m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Böttger, Erik C., Springer, Burkhard, Prammananan, Therdsak, Kidan, Yishak, Sander, Peter
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083859/
https://ncbi.nlm.nih.gov/pubmed/11306553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve062
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