Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations

To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an...

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Hlavní autoři: Sander, Peter, Springer, Burkhard, Prammananan, Therdsak, Sturmfels, Antje, Kappler, Martin, Pletschette, Michel, Böttger, Erik C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2002
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC127173/
https://ncbi.nlm.nih.gov/pubmed/11959546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1204-1211.2002
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