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Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations

To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an...

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Detalhes bibliográficos
Main Authors: Sander, Peter, Springer, Burkhard, Prammananan, Therdsak, Sturmfels, Antje, Kappler, Martin, Pletschette, Michel, Böttger, Erik C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC127173/
https://ncbi.nlm.nih.gov/pubmed/11959546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1204-1211.2002
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