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Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations

To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an...

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Bibliografske podrobnosti
Main Authors: Sander, Peter, Springer, Burkhard, Prammananan, Therdsak, Sturmfels, Antje, Kappler, Martin, Pletschette, Michel, Böttger, Erik C.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC127173/
https://ncbi.nlm.nih.gov/pubmed/11959546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.5.1204-1211.2002
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