Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations

To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an...

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Detalles Bibliográficos

Publicado en:	Antimicrob Agents Chemother
Autores principales:	Sander, Peter, Springer, Burkhard, Prammananan, Therdsak, Sturmfels, Antje, Kappler, Martin, Pletschette, Michel, Böttger, Erik C.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Mechanisms of Resistance
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1204-1211.2002
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