RecA-Mediated Gene Conversion and Aminoglycoside Resistance in Strains Heterozygous for rRNA

Clinical resistance to aminoglycosides in general is due to enzymatic drug modification. Mutational alterations of the small ribosomal subunit rRNA have recently been found to mediate acquired resistance in bacterial pathogens in vivo. In this study we investigated the effect of 16S rRNA heterozygos...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Prammananan, Therdsak, Sander, Peter, Springer, Burkhard, Böttger, Erik C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC89142/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10049249/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.43.3.447
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