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RecA-Mediated Gene Conversion and Aminoglycoside Resistance in Strains Heterozygous for rRNA

Clinical resistance to aminoglycosides in general is due to enzymatic drug modification. Mutational alterations of the small ribosomal subunit rRNA have recently been found to mediate acquired resistance in bacterial pathogens in vivo. In this study we investigated the effect of 16S rRNA heterozygos...

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Bibliografiske detaljer
Main Authors: Prammananan, Therdsak, Sander, Peter, Springer, Burkhard, Böttger, Erik C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC89142/
https://ncbi.nlm.nih.gov/pubmed/10049249
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