Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations

To study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides). We used a model system based on an...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Sander, Peter, Springer, Burkhard, Prammananan, Therdsak, Sturmfels, Antje, Kappler, Martin, Pletschette, Michel, Böttger, Erik C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC127173/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11959546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.5.1204-1211.2002
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