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Structural basis for selectivity and toxicity of ribosomal antibiotics
Ribosomal antibiotics must discriminate between bacterial and eukaryotic ribosomes to various extents. Despite major differences in bacterial and eukaryotic ribosome structure, a single nucleotide or amino acid determines the selectivity of drugs affecting protein synthesis. Analysis of resistance m...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1083859/ https://ncbi.nlm.nih.gov/pubmed/11306553 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve062 |
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