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β-TrCP recognizes a previously undescribed nonphosphorylated destruction motif in Cdc25A and Cdc25B phosphatases

β-TrCP, the F-box protein of the SCF(β-TrCP) ubiquitin ligase (SCF, Skp1/Cul1/F-box protein), recognizes the doubly phosphorylated DSG motif (DpSGΦXpS) in various SCF(β-TrCP) target proteins. The Cdc25A phosphatase, a key cell-cycle regulator in vertebrate cells, undergoes a rapid ubiquitin-dependen...

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Bibliografiske detaljer
Main Authors: Kanemori, Yoshinori, Uto, Katsuhiro, Sagata, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1083676/
https://ncbi.nlm.nih.gov/pubmed/15845771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501873102
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