ロード中...

Mode of Action of (1′S,2′R)-9-{[1′,2′-Bis(hydroxymethyl) cycloprop-1′-yl]methyl}guanine (A-5021) against Herpes Simplex Virus Type 1 and Type 2 and Varicella-Zoster Virus

The mode of action of (1′S,2′R)-9-{[1′,2′-bis(hydroxymethyl)cycloprop-1′-yl]methyl}guanine (A-5021) against herpes simplex virus type 1 (HSV-1), HSV-2, and varicella-zoster virus (VZV) was studied. A-5021 was monophosphorylated at the 2′ site by viral thymidine kinases (TKs). The 50% inhibitory valu...

詳細記述

保存先:
書誌詳細
主要な著者: Ono, Nobukazu, Iwayama, Satoshi, Suzuki, Katsuya, Sekiyama, Takaaki, Nakazawa, Harumi, Tsuji, Takashi, Okunishi, Masahiko, Daikoku, Tohru, Nishiyama, Yukihiro
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC105870/
https://ncbi.nlm.nih.gov/pubmed/9687413
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!