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A new nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxyl]methyl]guanine, highly active in vitro against herpes simplex virus types 1 and 2.

A novel nucleoside analog, 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]-guanine (BIOLF-62), was found to have potent antiviral activity against herpes simplex virus types 1 and 2 at concentrations well below cytotoxic levels. For example, the Patton strain of herpes simplex virus type 1 was suscept...

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Библиографические подробности
Главные авторы: Smith, K O, Galloway, K S, Kennell, W L, Ogilvie, K K, Radatus, B K
Формат: Artigo
Язык:Inglês
Опубликовано: 1982
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC183674/
https://ncbi.nlm.nih.gov/pubmed/6289741
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