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Assessment of a selective inhibitor of herpes simplex virus thymidine kinase (L-653,180) as therapy for experimental recurrent genital herpes.

Herpes simplex virus (HSV)-coded thymidine kinase (TK) is important in efficient reactivation of latent infection. These studies were designed to investigate whether treatment of latently infected animals with a TK inhibitor altered the natural history of recurrent HSV disease. 9-([(Z)-2-(hydroxymet...

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Dettagli Bibliografici
Autori principali: Bourne, N, Bravo, F J, Ashton, W T, Meurer, L C, Tolman, R L, Karkas, J D, Stanberry, L R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC192429/
https://ncbi.nlm.nih.gov/pubmed/1329638
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