Assessment of a selective inhibitor of herpes simplex virus thymidine kinase (L-653,180) as therapy for experimental recurrent genital herpes.

Herpes simplex virus (HSV)-coded thymidine kinase (TK) is important in efficient reactivation of latent infection. These studies were designed to investigate whether treatment of latently infected animals with a TK inhibitor altered the natural history of recurrent HSV disease. 9-([(Z)-2-(hydroxymet...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Bourne, N, Bravo, F J, Ashton, W T, Meurer, L C, Tolman, R L, Karkas, J D, Stanberry, L R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC192429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1329638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.36.9.2020
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