9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.

9-([2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (2'-nor-2'-deoxyguanosine; 2'NDG) selectively inhibits the replication of herpes group viruses. In cell culture studies 2'NDG was at least 10-fold more potent than acyclovir (ACV) in inhibition of human cytomegalovirus replication and Epstein-Barr...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Field, A K, Davies, M E, DeWitt, C, Perry, H C, Liou, R, Germershausen, J, Karkas, J D, Ashton, W T, Johnston, D B, Tolman, R L
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1983
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC394216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6306664/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.13.4139
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