9-([2-hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine: a selective inhibitor of herpes group virus replication.

9-([2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl)guanine (2'-nor-2'-deoxyguanosine; 2'NDG) selectively inhibits the replication of herpes group viruses. In cell culture studies 2'NDG was at least 10-fold more potent than acyclovir (ACV) in inhibition of human cytomegalovirus replicat...

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Detalhes bibliográficos
Main Authors: Field, A K, Davies, M E, DeWitt, C, Perry, H C, Liou, R, Germershausen, J, Karkas, J D, Ashton, W T, Johnston, D B, Tolman, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC394216/
https://ncbi.nlm.nih.gov/pubmed/6306664
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